Changes In DNA Due to cancer occur years ago, Research
Genetic system problems resulting from cancer often begin to occur several years ago, even decades ago.
This was revealed in international cancer research.
Genetic fingerprints of DNA damage caused by cancer have been revealed worldwide in a joint study by the Wellcome Sanger Institute, Duke NUS Medical School Singapore, University of California, Massachusetts Institute of Technology and Harvard University.
Scientists have compiled the most detailed genetic fingerprints ever made, indicating how each type of cancer is made in the body.
It will also help scientists discover unknown chemicals, biological pathways, and environmental factors that cause cancer.
The research, published in the journal Nature, is part of the Global Pan-Cancer Project, which aims to help understand cancer causes and formulate prevention strategies, while also making diagnosis and treatment therapeutic.
The 22 more research reports associated with the project were also published in the journal Nature, which took place in 37 countries around the world and analyzed more than 260 genomes in 38 different cell types.
Cancer undergoes genetic changes and the DNA of a single cell is transmitted uncontrollably to one to two more hundreds.
Past research reports have revealed that known causes of cancer, such as sun rays and smoking, are specific fingerprints of DNA destruction, which can help to understand how cancer spreads to the body, The extent to which it can spread and how to prevent it.
However, in the past, research reports were not large enough to identify all possible genetic signals.
This new research identified new gestures that had never been seen before and made them part of a larger database.
Researchers say that some types of DNA fingerprints reflect how cancer reacts to drugs, further research into how certain types of cancer can be effective and which drugs for them. Identification will help.
"The availability of large numbers of genomes will help us apply advanced analytical methods and expand research on further genetic defects," he said.
He added that this new repository will provide a much better picture of biological and chemical analysis of DNA damage or repair, allowing clinicians to determine the effects of cancer on the genome.